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6.10.2017 | Brianna Miers

Diazepam (Diastat) is drug intended for treatment of breakthrough seizures. It is primarily metabolized by CYP2C19 and CYP3A4, and genetic variability in.

This receptor is expressed in abundance in many peripheral organs and tissues as well as in the central nervous system, in the latter case, in glia cells. Diazepam, midazolam and flunitrazepam bind equally well to both the GABAa receptor and the peripheral BDZ receptor. Besides the GABAa receptor, BDZs also bind to the Peripheral Benzodiazepine Receptor (PBR); this receptor consists of several subunits, including the isoquinoline binding protein (TSPO, also referred to as a translocator protein); a voltage-dependent anion channel VDAC (VDAC1); an adenine nucleotide transporter ANT (SLC25A4); a PBR-associated protein 1 PRAX-1 (BZRAP1); and another PBR-associated protein PAP7 (ACBD3) [Articles:, 9504140, , , , ].


11.15.2017 | John Carrington

Sigma-Aldrich offers Sigma-D0899, Diazepam for your research needs. Find product specific information including CAS, MSDS, protocols and references.

Empirical Formula (Hill Notation) C 16 H 13 ClN 2 O Molecular Weight 284.74 EC Number MDL number MFCD.

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Keywords: Bioactive small molecules, Central Nervous System, Diseases, Metabolism, Neurodegenerative Diseases, Neuroscience, Neurotransmission, Neurotransmitters. The nervous system, comprised of the brain and spinal cord (central nervous system, or CNS) and network of nerves that connects the CNS to the rest of the body (peripheral nervous system, or PNS) is.

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Certificate of Analysis. This compound was developed by Roche. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

PubChem Substance ID.

Synonym: 7- Chloro- 1- methyl- 5- phenyl- 3H- 1,4- benzodiazepin- 2(1H) - one, Ro 5-2807 CAS Number.

Benzodiazepine anxiolytic; prototype ligand for the GABA A receptor benzodiazepine modulatory site.

D0899 - Diazepam.

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To browse other handbook pages, click here. This compound is featured on the GABAA Receptors page of the Handbook of Receptor Classification and Signal Transduction.

Diazepam Prices and Diazepam Coupons

4.8.2017 | Abigail Mackenzie

Compare prices and print coupons for Diazepam (Valium) and other Anxiety, Alcohol Addiction, Spasticity, and Musculoskeletal Conditions drugs at CVS.

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3.7.2017 | James Laird

Diazepam (plural diazepams). (pharmacology) A minor tranquillizer Noun[edit]. diazepam m (uncountable). (pharmacology) diazepam (minor tranquillizer).

From (benzo)diazep(ine) + -am of unknown origin.

diazepam ( plural diazepams ).

diazepam m ( uncountable ).

TripSit Factsheets

7.11.2017 | Noah Audley

Summary. A very common and widely prescribed benzodiazepine with hypnotic and sedative qualities. The metre by which other benzodiazepines are.