Learn about Oxycontin (Oxycodone HCl) may treat, uses, dosage, side effects, drug interactions, warnings, patient labeling, reviews, and.
The most common adverse reactions ( > 5%) reported by patients in clinical trials comparing OXYCONTIN with placebo are shown in Table 2 below:
OXYCONTIN should be prescribed only by healthcare professionals who are knowledgeable in the use of potent opioids for the management of chronic pain.
Injury, poisoning and procedural complications : accidental injury.
Accidental ingestion of even one dose of OXYCONTIN, especially by children, can result in a fatal overdose of oxycodone.
If the patient is currently taking a central nervous system (CNS) depressant and the decision is made to begin OXYCONTIN, start with 1/3 to ½ the recommended starting dosage of OXYCONTIN and monitor patients for signs of respiratory depression, sedation, and hypotension [see WARNINGS AND PRECAUTIONS, DRUG INTERACTIONS ]
The following serious adverse reactions are described elsewhere in the labeling:
Gastrointestinal disorders : abdominal pain, diarrhea, dyspepsia, gastritis.
Gastrointestinal disorders : dysphagia, eructation, flatulence, gastrointestinal disorder, increased appetite, stomatitis.
Metabolism and nutrition disorders : dehydration.
TABLE 2: Common Adverse Reactions ( > 5%) Adverse Reaction OXYCONTIN (n=227) (%) Placebo (n=45) (%) Constipation (23) (7) Nausea (23) (11) Somnolence (23) (4) Dizziness (13) (9) Pruritus (13) (2) Vomiting (12) (7) Headache (7) (7) Dry Mouth (6) (2) Asthenia (6) - Swe ating (5) (2).
Nervous system disorders : syncope, migraine, abnormal gait, amnesia, hyperkinesia, hypoesthesia, hypotonia, paresthesia, speech disorder, stupor, tremor, vertigo, taste perversion.
Although there has been no systematic assessment of such conversion, start with a conservative conversion: substitute 10 mg of OXYCONTIN every 12 hours for each 25 mcg per hour fentanyl transdermal patch.
Learn about Percocet (Oxycodone and Acetaminophen) may treat, uses, dosage, side effects, drug interactions, warnings, patient labeling.
Bottles of 100 NDC.
Proper assessment of the patient, proper prescribing practices, periodic re-evaluation of therapy, and proper dispensing and storage are appropriate measures that help to limit abuse of opioid drugs.
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Oxycodone can be abused in a manner similar to other opioid agonists, legal or illicit. Concerns about misuse, addiction, and diversion should not prevent the proper management of pain.
Oxycodone is a semisynthetic opioid synthesized from thebaine, an opioid alkaloid found in the Persian poppy, and one of the many alkaloids found in the.
Oxycodone is metabolized by the cytochrome P450 enzyme system in the liver, making it vulnerable to drug interactions. The dose of oxycodone must be reduced in patients with reduced hepatic function. Some people are fast metabolizers, resulting in reduced analgesic effect, but increased adverse effects, while others are slow metabolisers, resulting in increased toxicity without improved analgesia.
The chemical structures are very similar, differing only in that. Oxycodone's chemical name is derived from codeine.
In June 2015, then federal Minister of Health Rona Ambrose announced that within three years all oxycodone products sold in Canada would need to be tamper-resistant.
Find patient medical information for Oxycodone Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings.
A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching /swelling (especially of the face/ tongue /throat), severe dizziness, trouble breathing.
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If you have nausea, it may help to take this drug with food. You may take this drug with or without food.
Oxycodone is an opioid pain medication. An opioid is sometimes called a narcotic. Oxycodone is used to treat moderate to severe pain.
Fatal side effects can occur if you use this medicine with alcohol, or with other drugs that cause drowsiness or slow your breathing.
Take with food. Stop taking all other around-the-clock narcotic pain medicines when you start taking extended-release oxycodone.
Cancer patients with severe pain may require "as needed" rescue doses of the immediate-release form of oxycodone to supplement the controlled-release form. CR: 20 mg to 640 mg per day in patients with cancer pain. The average total daily dose is approximay 105 mg per day.